Monday, March 25, 2019

Neurological Disorders Journal- Lupine Publishers



Demyelinating diseases like Multiple Sclerosis and cases of long segment myelitis, neuromuscular disease' like Myasthenia Gravis'and Autoimmune Encephalitis have an autoimmune basis and occur in a relapsing remitting course. Achieving and maintaining remission in these patients is quite challenging. Steroids are used for maintaining remission, but its metabolic side effects ultimately are deleterious to the patient. Immunomodulators for remission and Gamma globulin for acute exacerbations are used but are an expensive mode of treatment. All patients may not be able to afford them.


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Monday, March 18, 2019

Neural Disorders Journal- Lupine Publishers



Objectives: The effects of Valproate sodium and placebo on global severity were compared in Child Autism Spectrum Disorders (ASD).
Materials and Methods: Childs with ASDs were enrolled in a 12-week double-blind placebo-controlled Valproate sodium trial. Fifty were randomly assigned to Valproate sodium (n=50) or placebo (n=50). The initial dose of Valproate sodium for children is 15mg/kg, then increases by 5-10mg/kg every week to 20-50mg/kg. Children are given 5% syrup (Sirupus Valproate sodium 5%), 1 ml 50mg. Repetitive behaviors were measured with the Clinical Global Impression (CGI) improvement scale.
Results: There was a significant treatment-by-time interaction indicating a significantly greater reduction in repetitive behaviors across time for Valproate sodium than for placebo. With overall response defined as a CGI global improvement score of 2 or less, there were significantly more responders at week 12 in the Valproate sodium group than in the placebo group. The risk ratio was 1.5 for CGI global improvement (responders: Valproate sodium, 80%; placebo, 12%). Side effects were not observed.
Conclusion: Valproate sodium treatment, compared to placebo, resulted in significantly greater improvement in global severity< behaviors, according to CGI rating scale. Valproate sodium appeared to be well tolerated movement score of 2 or less, there were significantly more responders at week 12 in the Valproate sodium group than in the placebo group. The risk ratio was 1.5 for CGI global improvement (responders: Acedipro, 80%; placebo, 12%). Side effects were not observed.


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Monday, March 11, 2019

Neurology Journals Impact Factor- Lupine Publishers


BPAN syndrome is a genetic disorder that progressively affects the nervous system and progressively worsens. People affected by this syndrome produce iron in the brain, which can be seen with medical imaging. For this reason, BPAN syndrome is classified with an impairment called Brain Neurodegeneration (NBIA) . 


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Thursday, March 7, 2019

Lupine Publishers: Lupine Publishes : Open Access Publisher

Lupine Publishers: Lupine Publishes : Open Access Publisher: Lupine Publishers Lupine Publishers    is a world’s leading Online Publishing repository, a  genuine publisher  with quality  medical jo...
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Wednesday, March 6, 2019

Journal of Neurology- Lupine Publishers



Neuroses and psychoses refer to clinical and nosographic problems. The terms psychoses and neuroses have long existed in the nosological vocabulary. Initially, they do not constitute a pair of opposites, they do not exclude themselves, they can overlap.Psychosis corresponds to mental illness, the psychiatric condition [1]. It is the technical concept to replace the term madness. In the nineteenth and early twentieth century, psychosis covered both mental disorders of organic origin, for example, “paralyticpsychosis” to designate general paralysis, such as functional diseases, ie delusions, as well as some mental disorders, like “obsessive psychosis”, which today could be called neurosis. The term neurosis is rather an aetiological and nosological concept, since the disorders are not based on the organic lesion. Psychoses without organic bases and not triggered by a toxic-infectious process could be considered neuroses.


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Lupine Publishers| Depression and Anxiety Frequency in Patients Hospitalized on the Guadalajara Regional Military Hospital in the Month of April 2019

  Lupine Publishers| Journal of Neurology and Brain Disorders   Abstract Observe and Identify patients that presented depression ...